Confinement of caspase-12 proteolytic activity to autoprocessing
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منابع مشابه
Correction for “ Con fi nement of caspase - 12 proteolytic activity to autoprocessing
BIOCHEMISTRY Correction for “Confinement of caspase-12 proteolytic activity to autoprocessing,” by Sophie Roy, Jeffrey R. Sharom, Caroline Houde, Thomas P. Loisel, John P. Vaillancourt, Wei Shao, Maya Saleh, and Donald W. Nicholson, which appeared in issue 11, March 18, 2008, of Proc Natl Acad Sci USA (105:4133–4138; first published March 10, 2008; 10.1073/pnas.0706658105). The authors note tha...
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Caspases are essential in animal programmed cell death both as initiator and executioner proteases. Plants do not have close caspase homologues, but several instances of caspase-like proteolytic activity have been demonstrated in connection with programmed cell death in plants. It was asked if caspase-like proteases are involved during development of the barley caryopsis. The presence of a casp...
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We previously demonstrated that tumour necrosis factor (TNF)-induced ceramide production by endosomal acid sphingomyelinase (A-SMase) couples to apoptosis signalling via activation of cathepsin D and cleavage of Bid, resulting in caspase-9 and caspase-3 activation. The mechanism of TNF-mediated A-SMase activation within the endolysosomal compartment is poorly defined. Here, we show that TNF-ind...
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The pathogenic mechanism(s) underlying neurodegenerative diseases associated with protein misfolding is unclear. Several studies have implicated ER stress pathways in neurodegenerative conditions, including prion disease, amyotrophic lateral sclerosis, Alzheimer's disease and many others. The ER stress response and upregulation of ER stress-responsive chaperones is observed in the brains of pat...
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BIOCHEMISTRY Correction for “Confinement of caspase-12 proteolytic activity to autoprocessing,” by Sophie Roy, Jeffrey R. Sharom, Caroline Houde, Thomas P. Loisel, John P. Vaillancourt, Wei Shao, Maya Saleh, and Donald W. Nicholson, which appeared in issue 11, March 18, 2008, of Proc Natl Acad Sci USA (105:4133–4138; first published March 10, 2008; 10.1073/pnas.0706658105). The authors note tha...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2008
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0706658105